Long-term macrolide antibiotics in asthma therapy
نویسندگان
چکیده
منابع مشابه
Macrolide therapy in asthma: limited treatment, long-term improvement.
As part of their interesting review of long-term macrolide therapy in chronic inflammatory airway diseases, CROSBIE and WOODHEAD [1] cite eight randomised double-blind placebocontrolled trials of macrolide therapy in asthma. Most were small, and all were short-term (none .12 weeks). Some positive effects were noted; mechanisms proffered included both anti-inflammatory and antimicrobial (includi...
متن کاملLow-dose, long-term macrolide therapy in asthma: An overview
Macrolides, a class of antimicrobials isolated from Streptomycetes more than 50 years ago, are used extensively to treat sinopulmonary infections in humans. In addition, a growing body of experimental and clinical evidence indicates that long-term (years), low (sub-antimicrobial)-dose 14- and 15-membered ring macrolide antibiotics, such as erythromycin, clarithromycin, roxithromycin and azithro...
متن کاملImmunomodulatory effects of macrolide antibiotics - part 2: advantages and disadvantages of long-term, low-dose macrolide therapy.
The available evidence for long-term, low-dose treatment with 14- and 15-membered ring macrolides in non-cystic fibrosis (CF) bronchiectasis, COPD, chronic sinusitis, and asthma is reviewed with special attention to possible adverse effects and the emergence of resistance during long-term macrolide treatment. Macrolide maintenance therapy has been proven to be of benefit in diffuse panbronchiol...
متن کاملImmunomodulatory Effects of Macrolide Antibiotics - Part 2: Advantages and Disadvantages of Long-Term, Low-Dose Macrolide Therapy
The available evidence for long-term, low-dose treatment with 14and 15-membered ring macrolides in non-cystic fibrosis (CF) bronchiectasis, COPD, chronic sinusitis, and asthma is reviewed with special attention to possible adverse effects and the emergence of resistance during long-term macrolide treatment. Macrolide maintenance therapy has been proven to be of benefit in diffuse panbronchiolit...
متن کاملImmunomodulatory Effects of Macrolide Antibiotics - Part 2: Advantages and Disadvantages of Long-Term, Low-Dose Macrolide Therapy
The available evidence for long-term, low-dose treatment with 14and 15-membered ring macrolides in non-cystic fibrosis (CF) bronchiectasis, COPD, chronic sinusitis, and asthma is reviewed with special attention to possible adverse effects and the emergence of resistance during long-term macrolide treatment. Macrolide maintenance therapy has been proven to be of benefit in diffuse panbronchiolit...
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ژورنال
عنوان ژورنال: Reviews in Health Care
سال: 2011
ISSN: 2038-6702,2038-6699
DOI: 10.7175/rhc.6124243-258